Facile synthesis of oligoyne amphiphiles and their rotaxanes.

Facile synthesis of oligoyne amphiphiles and their rotaxanes† †Electronic supplementary information (ESI) available: Fig. S1–S4 and a comprehensive account of all experimental details, including synthetic procedures, analytical data, and NMR spectra of all novel compounds. See DOI: 10.1039/c4sc03154g Click here for additional data file.

Synthesis of fumaramide derived [3]rotaxanes as potential precursors for molecular boxes.

Three new fumaramide-derived [3]rotaxanes have been synthesized, with the aim of macrocycle linking to form a molecular box. In one case, a nine-component templated [3]rotaxane synthesis was accomplished in 40% yield. Rotaxane reduction resulted in an unexpectedly facile de-slipping process.

Macrocyclic shape-persistency of cyclo[6]aramide results in enhanced multipoint recognition for the highly efficient template-directed synthesis of rotaxanes.

Examples of using two-dimensional shape-persistent macrocycles, i.e. those having noncollapsible and geometrically well-defined skeletons, for constructing mechanically interlocked molecules are scarce, which contrasts the many applications of these macrocycles in molecular recognition and functional self-assembly. Herein, we report the crucial role played by macrocyclic shape-persistency in en...

Facile one-pot synthesis of pyrimido[4,5-d]pyrimidine-2,4-diones in Ionic Liquid and study of their antibacterial activities

A simple, novel, efficient and three-component procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives by the reaction of 6-amino-1,3-dimethyluracil, aldehyde and 2-benzylisothiourea hydrochloride promoted by ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIm]Br) under solvent-free conditions is reported. The presented method is benefited from operational simplicity...

Facile one-pot synthesis of pyrimido[4,5-d]pyrimidine-2,4-diones in Ionic Liquid and study of their antibacterial activities

A simple, novel, efficient and three-component procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives by the reaction of 6-amino-1,3-dimethyluracil, aldehyde and 2-benzylisothiourea hydrochloride promoted by ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIm]Br) under solvent-free conditions is reported. The presented method is benefited from operational simplicity...